Lorine
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lorine
Did you have any side effects with this medicine?
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sponsoredWhat is Lorine?
Lorine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Lorine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.
Lorine is also used to treat skin hives and itching in people with chronic skin reactions.
Lorine may also be used for purposes not listed in this medication guide.
Lorine indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.sponsored
Treatment of seasonal allergic rhinitis, perennial rhinitis, urticaria, allergic dermatologic disorders, angioedema and conjunctivitis. Lorine is generally considered to be ineffective in asthma.
Acute anaphylaxis should be treated with adrenaline; Lorine and corticosteroids are given to prevent relapse.
Lorine is also used to control the pruritus associated with skin disorders eg, atopic eczema.
How should I use Lorine?
Use Lorine orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take Lorine orally disintegrating tablets by mouth with or without food. Be sure that your hands are completely dry before you handle Lorine orally disintegrating tablets. Use the tablet right away after you remove it from the tablet blister. To open the tablet blister, peel back the foil, then gently remove the tablet. Place the tablet on the tongue. The tablet will dissolve quickly. You may take Lorine orally disintegrating tablets with or without water. If you miss a dose of Lorine orally disintegrating tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.Ask your health care provider any questions you may have about how to use Lorine orally disintegrating tablets.
Uses of Lorine in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.sponsored
This medication is an antihistamine that treats symptoms such as itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergies. It is also used to relieve itching from hives.
Lorine does not prevent hives or prevent/treat a serious allergic reaction (e.g., anaphylaxis). Therefore, if your doctor has prescribed epinephrine to treat allergic reactions, always carry your epinephrine injector with you. Do not use Lorine in place of your epinephrine.
If you are self-treating with this medication, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.
Do not use this medication in children younger than 6 years unless directed by the doctor.
How to use Lorine
If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. If your doctor has prescribed this medication, follow your doctor's directions and the instructions on your prescription label. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor or the product package, usually once or twice a day. Remove the tablet from its foil pack immediately before taking and place the tablet on the tongue. It will dissolve quickly. You may swallow the dissolved medication with or without water. Dosage is based on your age, condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age.
Tell your doctor if your allergy symptoms do not improve after 3 days of treatment or if your hives last more than 6 weeks. Seek immediate medical attention if your condition worsens or you think you have a serious medical problem (e.g., very serious allergic reaction/anaphylaxis).
Lorine description
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Lorine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. Lorine's anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease.
Lorine dosage
Applies to the following strength(s): 10 mg; 5 mg/5 mL; 5 mg
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Allergic Rhinitis UrticariaUsual Pediatric Dose for:
Allergic Rhinitis UrticariaAdditional dosage information:
Renal Dose Adjustments Liver Dose Adjustments DialysisUsual Adult Dose for Allergic Rhinitis
10 mg orally once a day
Usual Adult Dose for Urticaria
10 mg orally once a day
Usual Pediatric Dose for Allergic Rhinitis
2 to 5 years: 5 mg orally once a day (syrup)
6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)
Usual Pediatric Dose for Urticaria
2 to 5 years: 5 mg orally once a day (syrup)
6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)
Renal Dose Adjustments
CrCl less than 30 mL/min: administer dosage every other day initially
Liver Dose Adjustments
Liver failure: administer dosage every other day initially
Dialysis
Lorine is not significantly removed by hemodialysis, thus supplementary dosing is not required following hemodialysis.
More about Lorine
Side EffectsDuring Pregnancy or BreastfeedingDosage InformationDrug ImagesDrug InteractionsSupport GroupPricing CouponsEn Espanol43 Reviews - Add your own review/ratingConsumer resources
LorineLorine capsulesLorine chewable tabletsLorine orally disintegrating tabletsLorine syrupOther brands: Claritin, Alavert, Wal-itin, Claritin 24 Hour Allergy, More (7) »Professional resources
Lorine (AHFS Monograph)More (4) »Related treatment guides
Allergic RhinitisUrticariaLorine interactions
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What other drugs will affect Lorine?
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Lorine (10 mg once daily) has been coadministered with therapeutic doses of erythromycin, cimetidine, and ketoconazole in controlled clinical pharmacology studies in adult volunteers. Although increased plasma concentrations (AUC 0-24 hrs) of Lorine and/or descarboethoxyloratadine were observed following coadministration of Lorine with each of these drugs in normal volunteers (n = 24 in each study), there were no clinically relevant changes in the safety profile of Lorine, as assessed by electrocardiographic parameters, clinical laboratory tests, vital signs, and adverse events. There were no significant effects on QTc intervals, and no reports of sedation or syncope. No effects on plasma concentrations of cimetidine or ketoconazole were observed. Plasma concentrations (AUC 0-24 hrs) of erythromycin decreased 15% with coadministration of Lorine relative to that observed with erythromycin alone. The clinical relevance of this difference is unknown. These above findings are summarized in TABLE 1.
TABLE 1 Effects on Plasma Concentrations (AUC 0-24 hrs) of Lorine and Descarboethoxyloratadine After 10 Days of Coadministration (Lorine 10 mg) in Normal Volunteers Lorine Descarboethoxyloratadine Erythromycin (500 mg q8h) 40% 46% Cimetidine (300 mg qid) 103% 6% Ketoconazole (200 mg q12h) 307% 73%Lorine side effects
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What are the possible side effects of Lorine?
Applies to Lorine: oral fixed-combination tablets, oral orally disintegrating tablets, oral solution, oral tablets
Side effects include:
Children 2–5 years of age receiving oral solution: Diarrhea, epistaxis, pharyngitis, flu-like symptoms, fatigue, stomatitis, tooth disorder, earache, viral infection, rash.
Children 6–12 years of age receiving oral solution: Nervousness, wheezing, fatigue, hyperkinesia, abdominal pain, conjunctivitis, dysphonia, upper respiratory tract infection.
Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth.
Fixed combination Lorine (the active ingredient contained in Lorine Reditab) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.
Lorine contraindications
See also:
What is the most important information I should know about Lorine?
Do NOT use Lorine if:
you are allergic to any ingredient in Lorine
Contact your doctor or health care provider right away if any of these apply to you.
Active ingredient matches for Lorine:
Loratadine in Oman.
Risedronic acid in Romania.
List of Lorine substitutes (brand and generic names)
Sort by popularity Unit description / dosage (Manufacturer)Price, USD Lorin-nsa (Pakistan) Lorinet (Vietnam) Lorinet 10 mg x 10 Blister x 10 Tablet Lorinol (India, Myanmar) Lorinol 10mg TAB / 10 (Micro Gratia)$ 0.65 10 mg x 10's (Micro Gratia)$ 0.65 LORINOL CREAM 1 tube / 15 GM cream each (Micro Gratia)$ 2.41 LORINOL EYE DROP 1 packet / 5 ML eye drop each (Micro Gratia)$ 1.51 LORINOL TABLET 1 strip / 10 tablets each (Micro Gratia)$ 1.13 LORINOL tab 10 mg x 10's (Micro Gratia)$ 0.65 Lorinol NA Cream (Micro Gratia)$ 2.41 Lorinol NA Eye Drop (Micro Gratia)$ 1.51 Lorinol 10mg Tablet (Micro Gratia)$ 0.11 Lorinol-10 (Myanmar) Lorinol-10 chewable tab 10 mg 10 x 10's (Micro Labs) LORISPA (India) 10 mg x 100's (Sidhbali)$ 5.08 Lorispa 10mg TAB / 100 (Sidhbali)$ 5.08 LORISPA tab 10 mg x 10's (Sidhbali)$ 0.51 Lorispa 10mg TAB / 100 (Sidhbali)$ 5.08 Loristal (Peru) LORIT LORIT 10MG TABLET 1 strip / 10 tablets each (Wizad Biotech Pvt Ltd)$ 0.63 Lorita (Thailand) Lorita 10 mg x 10 x 10's (Bangkok Lab Cosmetic) Lorita tab 10 mg 10 x 10's (Bangkok Lab Cosmetic) Loritab (Myanmar) Loritex (Peru) Loritil (Brazil) Loritin (Iceland, Malta, Taiwan) Loritin 10 mg (Actavis) Loritine (Turkey) Lorityne (Thailand) LORKIND (India) 10 mg x 100's (Elfin (Biotropics)) Lorkind 10mg MD-TAB / 100 (Elfin (Biotropics)) LORKIND MD- tab 10 mg x 10's (Elfin (Biotropics)) Lorkind 10mg MD-TAB / 100 (Elfin (Biotropics)) LORLY (India) 10 mg x 10's (Zodley)$ 0.60 Lorly 10mg TAB / 10 (Zodley)$ 0.60 LORLY tab 10 mg x 10's (Zodley)$ 0.60 Lorly 10mg TAB / 10 (Zodley)$ 0.60 Lormeg (Myanmar, South Africa) Lormeg 10mg TAB / 10 (Alembic)$ 0.51 Lormeg 5mg/mL SYR / 30ml (Alembic)$ 0.40 Lormeg 10 mg x 10 Blister x 10 Tablet (Alembic) 10 mg x 10's (Alembic)$ 0.51 5 mg x 30ml (Alembic)$ 0.40 LORMEG 10 MG TABLET 1 strip / 10 tablets each (Alembic)$ 0.61 LORMEG tab 10 mg x 10's (Alembic)$ 0.51 LORMEG syr 5 mg x 30ml (Alembic)$ 0.40See 2363 substitutes for Lorine
References
DailyMed. "LORATADINE; PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018). PubChem. "loratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018). DrugBank. "loratadine". http://www.drugbank.ca/drugs/DB00455 (accessed September 17, 2018).Reviews
The results of a survey conducted on ndrugs.com for Lorine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Lorine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Lorine drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost. Users% Not expensive1100.0%
Consumer reported time for results
No survey data has been collected yet7 consumers reported age
Users% 1-5457.1% 30-45114.3% 114.3% 6-15114.3%Consumer reviews
There are no reviews yet. Be the first to write one!
Information checked by Dr. Sachin Kumar, MD Pharmacology
По данным ВОЗ, нежелательные реакции классифицированы в соответствии с их частотой развития следующим образом: очень часто (≥1/10), часто (≥1/100,
Со стороны иммунной системы: очень редко — анафилактические реакции.
Со стороны нервной системы: часто — головная боль, сонливость, повышенная нервная возбудимость, повышенная утомляемость; нечасто — бессонница; очень редко — головокружение.
Со стороны ССС: очень редко — тахикардия, учащенное сердцебиение, синкопе, аритмия.
Со стороны ЖКТ: нечасто — повышение аппетита; очень редко — тошнота, сухость во рту, гастрит.
Со стороны печени и желчевыводящих путей: очень редко — нарушение функции печени.
Со стороны кожных покровов: очень редко — аллергические реакции (сыпь), алопеция.
Кроме выше перечисленных реакций, у детей возможно развитие седативного эффекта. Нежелательные явления со стороны ЦНС (головная боль, сонливость, повышенная утомляемость) встречались приблизительно с той же частотой, что и при применении плацебо («пустышки»).
